Protective effect of royal jelly on the sperm parameters and testosterone level and lipid peroxidation in adult mice treated with oxymetholone

نویسندگان

  • Ensieh Zahmatkesh Department of Histology and Embryology, Faculty of Science, Urmia University, Urmia, I. R. Iran
  • Gholamreza Najafi Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Urmia University, Urmia, I. R. Iran
  • Reza Heidari Department of Biochemistry, Faculty of Science, Urmia University, Urmia, I. R. Iran
  • Vahid Nejati Department of Histology and Embryology, Faculty of Science, Urmia University, Urmia, I. R. Iran
چکیده مقاله:

Objectives: The aim of the present study was to evaluate protective effect of royal jelly on sperm parameters, testosterone level, and malondialdehyde (MDA) production in mice. Materials and Methods: Thirty-two adult male NMRI mice weighing 30±2 g were used. All the animals were divided into 4 groups. Control group: received saline 0.1 ml/mouse/day orally for 30 days. Royal Jelly group (RJ): received royal jelly at dose of 100 mg/kg daily for 30 days orally. Oxymetholone group: the received Oxymetholone (OX) at dose of 5 mg/kg daily for 30 days orally. Royal Jelly+Oxymetholone group: received royal jelly at dose of 100 mg/kg/day orally concomitant with OX administration. Sperm count, sperm motility, viability, maturity, and DNA integrity were analyzed. Furthermore, serum testosterone and MDA concentrations were determined. Results: In Oxymetholone group, sperm count, motility as well as testosterone concentration reduced significantly (p

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protective effect of royal jelly on the sperm parameters and testosterone level and lipid peroxidation in adult mice treated with oxymetholone

objectives: the aim of the present study was to evaluate protective effect of royal jelly on sperm parameters, testosterone level, and malondialdehyde (mda) production in mice. materials and methods: thirty-two adult male nmri mice weighing 30±2 g were used. all the animals were divided into 4 groups. control group: received saline 0.1 ml/mouse/day orally for 30 days. royal jelly group (rj): re...

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protective effect of royal jelly on in vitro fertilization (ivf) in male mice treated with oxymetholone

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عنوان ژورنال

دوره 4  شماره 1

صفحات  43- 52

تاریخ انتشار 2014-01-01

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